College of Veterinary Medicine

 

Understanding the Host Response to Infection

VCM 562 | 3 credit hours

Contact Information

Instructor: Dr. Brian Aldridge
Email: ba311@illinois.edu

Course Description

This is an 8-week graduate level course that provides a framework for understanding the anatomical, physiological, immunological, microbiological, and pathological basis of health maintenance in the major body systems impacted by infectious disease. The course will use a case-based approach to train students how to apply the basic principles of health science in solving clinical problems in individual animals that are part of a livestock production system. The instructors assume that enrolled students have a foundational knowledge in microbiology and livestock system operations.

This course will take 7-9 hours per week (estimate includes lectures, readings, assignments, etc).

Mode of Teaching

This course is fully online using Compass 2g (https://compass2g.illinois.edu) supported by Blackboard. The content will be presented as text, videos, and other media. The course covers the same amount of material that would be expected if the class were a traditional campus-based course. Due to the nature of online learning, students must be diligent about their learning, engaging often and actively.

Course Goals

Students will develop a strong foundation in a clinical problem solving approach that applies the basic principles of health science in the investigation of respiratory, gastrointestinal, reproductive and systemic health problems in individual animals that are part of a livestock production system. Students will be challenged to use this approach in formulating rational diagnostic, prognostic, therapeutic and preventative management plans for optimizing the health, welfare and productivity of a range of livestock species.

Learning Objectives

Upon successful completion of this course, students will be able to:

  • Understand the process of applying basic principles of health science in solving livestock health problems.
  • Apply a rational, systematic, data-informed approach for investigating health challenges and failure in different body systems, at both an individual and population level.
  • Use a problem-based approach to develop health protocols that can be used to identify, monitor, and respond to health problems for a particular body system in a specific livestock context.

Module Topics

  • Module 1: Quantifying Disruptions in Animal Health
    • Defining diseases
    • Improved thinking: the whole and the parts
    • Quantifying disturbances in animal health: employing the optimal problem-solving approach
    • Quantifying disturbances in animal health: enhanced case definition
    • Quantifying disturbances in animal health: quizzical quadrangle
  • Module 2: Principles and Challenges to Health Defense
    • Immunity: the conductor of homeostasis
    • Inflammation: the root of homeostasis
    • Mucosa: battle site of homeostasis
    • Stress: disruptor of homeostasis
    • Mucosal stress
    • Metabolic and microbial stress
    • Microbes: threats to homeostasis
    • Modes and mechanisms of different categories of pathogens
    • Bacterial pathogens
    • Viral, protozoal and parasite pathogenesis
  • Module 3: Challenges to Respiratory Health
    • Maintenance of respiratory health
    • Failure of respiratory health
    • Clinical problems –respiratory health failure in individual animals within a livestock production system
  • Module 4: Challenges to Gastrointestinal Health
    • Maintenance of gastrointestinal health
    • Failure of gastrointestinal health
    • Clinical problems –gastrointestinal health failure in individual animals within a livestock production system
  • Module 5: Challenges to Reproductive Health
    • Maintenance of reproductive system health
    • Failure of reproductive health
    • Clinical problems –gastrointestinal health failure in individual animals within a livestock production system
  • Module 6: Challenges to Systemic Health
    • Maintenance of systemic health
    • Failure of systemic health
    • Clinical problems - systemic health failure in individual animals within a livestock production system
  • Module 7: Health Protocols
    • Identifying health failure
    • Responding to health failure
    • Monitoring health failure

Course Requirements

Required Textbooks

  • There is no required textbook

Technical Requirements

  • A reliable device.
  • High-speed internet connection: e.g. DSL or Cable.
  • Supported web browser: e.g. a recent version of Google Chrome, Firefox, or Safari.
  • Access Microsoft Office 365 (Net ID and password needed) & have Adobe Acrobat Reader installed.
  • Minimum technical skills: At a minimum, students must possess the ability to navigate Blackboard.  This includes accessing course content, posting to a discussion board, and completing online assignments, quizzes, self-assessments, and exams.
  • Online meetings via ZOOM: We use a software solution called ZOOM for online meetings. Student may join from PC, Mac, Linux, iOS or Android or call by telephone. The meeting link or telephone number will be provided after meeting is scheduled to join a meeting. A webcam is preferred for easier communication.